Preheat your oven to 375. Place your ground meats in a large bowl.
Cube your bread and place in a separate bowl along with the 1/4 cup milk pressing down to soak all the bread. Let the bread cubes and milk sit for a few minutes to get soft.
After your bread has softened, add the eggs.
Combine the eggs with the milk and pour over your ground meats. Add your garlic, salt and pepper, parsley, oregano, grated parmesan cheese to your meats, bread and egg mixture.
Mix with your hands or a rubber spatula until well combined. The mixture is going to be soft, but not too soft to form into your meatballs. If you feel it may be too loose, add a little bread crumbs.
Roll your meatballs, small, medium or large, whatever your preference is and place on a sheet pan. Place in the preheated oven and cook for about 25 minutes.
after the 25 minutes, remove from the oven.
Put the meatballs in the sauce, pushing down to cover. If using the Instant Pot, set for 10 minutes, then do a quick release of pressure to release the steam. If you are cooking on the stove top, add your meatballs to the sauce and simmer for about 20 minutes.